Daniel

Rachel Bitterman

Luc Fromage

Glenn

Daniel's 'Boss'

Himself

Herself

Joe Snow (voice)

Nancy Nut-What

Sally Ann Santa Claus

Kermit the Frog / Rizzo the Rat / Beaker / Elvises (voice)

The Great Gonzo / Dr. Bunsen Honeydew / Waldorf / Zoot (voice)

Pepe the King Prawn / Bobo the Bear / Johnny Fiama / Swedish Chef / Lew Zealand / Howard Tubman / Rowlf the Dog / Elvises (voice)

Miss Piggy / Fozzie Bear / Animal / Yoda / Elvises (voice)

Scooter / Janice / Sal Minella (voice)

Sam Eagle (voice)

Sweetums (voice)

Robin the Frog / Statler / Floyd Pepper / Announcer / Crazy Harry / Pops

Eugene the Tuba Player (voice)

Muppet Performer

Dr. John "J.D." Dorian

Dr. Elliot Reid

Janitor

Dr. Perry Cox

Nurse Carla Espinosa

Triumph, the Insult Comic Dog (voice)

Dr. Teeth (voice)

Security Guard